Jessica Gibson 26 April 2026

Jessica Gibson

DoctoriumGP Body Composition Report — Scan 4 of 4

Age 36 166 cm Female DOB: 28/09/1989 Trajectory Reversed
Weight
90.4kg
−1.8 kg vs baseline
Body Fat
38.1%
−1.6% vs baseline
Muscle Mass
53.1kg
+0.3 kg vs baseline

Trajectory Has Reversed — Interventions Are Working

Following the 12 April consultation and adjusted protocol, Jessica’s body composition has shifted decisively in the right direction. Over the 28 days between Scan 2 (29 Mar) and Scan 4 (26 Apr), weight has dropped by −2.0 kg, body fat has fallen −2.1%, fat mass is down −2.6 kg, and — critically — muscle mass has increased by +0.6 kg. This is exactly the high-quality fat loss we were targeting: visceral and limb fat coming off while lean tissue is preserved and gained. The plateau identified in late March has broken; the suspected metabolic blocker appears to be responding to the revised approach.

−2.0 kg in 28 Days −2.6 kg Fat Mass +0.6 kg Muscle Gained Body Fat −2.1% Quality Loss — Lean Mass Preserved

Metabolic Age

51
Metabolic Age

Chronological Age

36
Born 28 September 1989

Metabolic Age

51
15 years above chronological age

BMR

1,705kcal
7,134 kJ — daily resting energy
+15 years above actual age — next focus area as fat loss continues
Body Composition

Key Metrics

Scan 4 (26 Apr 2026) — 56 days since baseline, four scans tracked

Key Metrics

Weight
90.4kg
Baseline: 92.2 kg — Scan 2: 92.4 kg
−1.8 kg
Body Fat
38.1%
Baseline: 39.70% — Scan 2: 40.20%
−1.6%
Fat Mass
34.5kg
Baseline: 36.60 kg — Scan 2: 37.10 kg
−2.1 kg
Muscle Mass
53.1kg
Baseline: 52.80 kg — Scan 2: 52.50 kg
+0.3 kg
Fat-Free Mass
55.9kg
Baseline: 55.6 kg — Scan 2: 55.3 kg
+0.3 kg
BMI
32.8
Baseline: 33.40 — Class I Obese (BMI inflated by muscle)
−0.6
Visceral Fat
8
Rating: Average (1-12 = Healthy)
Unchanged
Total Body Water
42.5%
38.42 kg — Baseline: 41.80%
+0.7%

Body Composition Breakdown

38.1% Fat
58.7% Muscle
3.1% Bone
Fat Mass: 34.5 kg
Muscle Mass: 53.1 kg
Bone Mass: 2.8 kg
Body Fat Percentage 38.1%
Healthy: 21-33%Current: Over Fat (improving)
Muscle Mass 53.1 kg
Above average for age/height58.7% of total — gaining
Total Body Water 42.5%
Healthy: 45-60%Trending upward
Visceral Fat Rating 8
Healthy: 1-12Stable
Bone Mass 2.8 kg
Expected: 2.4-3.0 kgNormal
Protein 14.68 kg
16.2% of total mass — up from 14.8%
Under
Normal
Over
Obese I
Obese II
Obese III
32.8
18.525.030.035.040.050+
Physique Rating: Solidly-Built (Over Fat — trending toward Standard Muscular)
Clinical Analysis

Scan Comparison

56-day trajectory across four scans — Baseline through latest

Percentile Rankings

vs UK Women Age 30–39
15th
%ile

Body Fat %

At 38.1%, Jessica still carries more body fat than ~85% of UK women her age, but the trend is now moving in the right direction — down from 40.2% in late March. The desirable range remains 23–34%; current trajectory suggests she will breach the "Over Fat" threshold within 8–10 weeks if the protocol is maintained.

92nd
%ile

Muscle Mass

53.1 kg of muscle mass is exceptional — higher than ~93% of UK women aged 30–39 and up +0.6 kg in 28 days. Lean tissue has not just been preserved during fat loss — it has actively grown. This is the gold standard outcome.

8th
%ile

Metabolic Age

Metabolic age remains at 51 (vs chronological 36) — this lags body composition by 8–12 weeks and is expected to begin shifting once the new fat-loss trajectory is sustained. It remains the next priority area to target.

20th
%ile

BMI

At 32.8 (down from 33.5), Jessica still sits in Obese Class I, but BMI is a misleading metric here — her exceptional muscle mass inflates this figure significantly. Body fat percentage and segmental analysis give a more accurate clinical picture.

55th
%ile

Visceral Fat

Visceral fat rating remains stable at 8 — within the healthy range (1–12) but sits mid-table for women her age. With overall fat mass now falling, this number is expected to begin trending down at the next scan. The trunk fat reduction (35.6% → 33.0%) suggests visceral fat is already starting to mobilise.

35th
%ile

Leg Muscle Score

Scoring ~70 on the Tanita leg muscle scale, Jessica remains below average for her age. Despite strong overall muscle mass, lower body remains a relative weakness. Targeted lower body resistance work (squats, hip hinges, lunges) is the highest-leverage addition to lock in the metabolic momentum.

Scan Comparison & Trajectory

Metric Scan 1
1 Mar
Scan 2
29 Mar
Scan 3
12 Apr
Scan 4
26 Apr
Δ vs Baseline
Weight 92.2 kg 92.4 kg 91.6 kg 90.4 kg −1.8 kg
Body Fat % 39.70% 40.20% 39.80% 38.10% −1.6%
Fat Mass 36.60 kg 37.10 kg 36.50 kg 34.50 kg −2.1 kg
Muscle Mass 52.80 kg 52.50 kg 52.30 kg 53.10 kg +0.3 kg
FFM 55.6 kg 55.3 kg 55.1 kg 55.9 kg +0.3 kg
BMI 33.40 33.50 33.20 32.80 −0.6
BMR 1,704 kcal 1,697 kcal 1,691 kcal 1,705 kcal +1 kcal
Visceral Fat 8 8 8 8 Unchanged
TBW % 41.80% 42.00% 42.10% 42.50% +0.7%
Metabolic Age 51 51 51 51 Unchanged

Scan 1 — Baseline

1 March 2026
Weight92.2 kg
Body Fat39.70%
Fat Mass36.60 kg
FFM55.6 kg
Muscle Mass52.80 kg
BMI33.40
Metabolic Age51
BMR1,704 kcal
Visceral Fat8
TBW41.80%
Bone Mass2.80 kg

Scan 4 — Latest

26 April 2026
Weight90.4 kg
Body Fat38.10%
Fat Mass34.50 kg
FFM55.9 kg
Muscle Mass53.10 kg
BMI32.80
Metabolic Age51
BMR1,705 kcal
Visceral Fat8
TBW42.50%
Bone Mass2.80 kg

56-Day Changes (Baseline → Latest)

Weight−1.8 kg
Body Fat−1.6%
Fat Mass−2.1 kg
Muscle Mass+0.3 kg
FFM+0.3 kg
BMI−0.6
BMR+1 kcal
TBW+0.7%
Metabolic AgeUnchanged (51)
Visceral FatUnchanged (8)
Acceleration in latest 28 days: Between Scan 2 (29 Mar) and Scan 4 (26 Apr), weight dropped −2.0 kg, fat mass −2.6 kg and muscle mass increased +0.6 kg — the inflection point is clear and recent.

Segmental Analysis

SegmentMassRatingStatus
Trunk 31.7 kg 3 High
Left Arm 2.7 kg 1 Average
Right Arm 2.7 kg 1 Average
Left Leg 7.8 kg 0 Average
Right Leg 8.2 kg 1 Average
Both arms gained +0.2 kg of muscle since Scan 2 — arms are now symmetrical at 2.7 kg.
SegmentFat %MassStatus
Trunk 33.0% 16.4 kg Improved
Left Arm 41.6% 2.0 kg Improving
Right Arm 42.1% 2.0 kg Improving
Left Leg 46.0% 7.1 kg Avg-High
Right Leg 44.6% 7.0 kg Avg-High
Trunk fat −1.8 kg, arm fat −0.3 kg combined — the visceral/upper-body fat is mobilising first, which is the metabolically meaningful loss.
Left Arm
41.6%
2.7 kg muscle
Right Arm
42.1%
2.7 kg muscle
Trunk
33.0%
31.7 kg muscle
Left Leg
46.0%
7.8 kg muscle
Right Leg
44.6%
8.2 kg muscle
Treatment History

Treatment History

Medications, products, and appointment timeline

Medications & Treatment History

Tirzepatide 10 mg (15 mg pen)

GLP-1 receptor agonist — held at 10 mg following Scan 4 review
Prescribed 14 Sep 2025 by Dr Gemma Lewis
Responding Hold at 10 mg

Nitrofurantoin 100 mg MR

14 capsules, BD, PO, 7 days — Antibiotic (UTI)
Prescribed 11 Oct 2025 by Dr Gemma Lewis
C E Ferulic 30ML
1 Mar 2026
Glycolic Cleanser 150ml
2 Nov 2025
Phyto Corrective Serum 30ML
2 Nov 2025
26 Apr 2026
Body Composition Scan + Private GP Review
Today — Scan 4 • Trajectory confirmed
12 Apr 2026
Body Composition Scan + Body Concerns Consultation
Scan 3 • Protocol adjustments agreed
29 Mar 2026
Body Composition Scan
Scan 2 • Plateau identified
01 Mar 2026
Body Composition Scan
Scan 1 • Baseline established
22 Nov 2025
Body Concerns Consultation
02 Nov 2025
Aesthetic Consultation
11 Oct 2025
Body Concerns Consultation
Cancelled — Sickness
11 Oct 2025
Private GP Appointment
21 Sep 2025
Body Concerns Consultation
Blood pressure check
14 Sep 2025
Weight Loss Medical Clinic
Initial consultation — Tirzepatide started
Clinical Assessment

Clinical Assessment

Trajectory has shifted — protocol working, refine and continue

Clinical Assessment

Trajectory Update — Inflection Point Confirmed

The plateau identified in late March has broken decisively. Across the 28 days between Scan 2 and Scan 4, Jessica has lost 2.0 kg of weight, 2.6 kg of fat mass and gained 0.6 kg of muscle. This is the high-quality body recomposition we were targeting — lean tissue is being preserved (and added) while visceral and limb fat are mobilising. The protocol adjustments agreed at the 12 April consultation are working.

The clinical priority now shifts from “investigate metabolic blocker” to “sustain and amplify what is working.” Continue current pharmacological and lifestyle protocol, layer in targeted lower-body resistance training to address the leg muscle score, and re-test at Scan 5 in late May to confirm trajectory.

GL

Dr Gemma Lewis MRCS MRCGP — Clinical Opinion

Clinical Director, DoctoriumGP • 26 April 2026

Working Diagnosis Holds — Targeted Protocol Is Working

The PCOS / insulin resistance picture remains the most likely underlying mechanism, but Scan 4 confirms that the combined approach — tirzepatide at 10 mg, insulin-sensitising support, addressing methylation, and lifestyle adjustments — is now producing the expected response. We do not need to escalate the GLP-1 dose at this time. Continue current protocol, await final blood and methylation results, and refine where indicated.

Tirzepatide Response

After the protocol pivot, the GLP-1 is now producing the expected effect: appetite regulation, fat-preferential loss, and lean mass preservation. Holding at 10 mg is appropriate — no escalation needed while the current trajectory continues.

Quality of Loss

Muscle mass increased +0.6 kg while fat dropped −2.6 kg. This is unusual on GLP-1 monotherapy — it suggests the protein, training and supplementation layer is doing meaningful work. Protect this signal: do not under-eat protein, do not skip resistance sessions.

Trunk Fat Mobilising

Trunk fat % has dropped from 35.6% to 33.0% in 28 days — a meaningful shift in the most metabolically active depot. Visceral fat rating remains 8 (lags trunk %) but is expected to step down at the next scan. Continued reduction here directly improves cardiometabolic risk.

Outstanding: Metabolic Age & Legs

Metabolic age remains at 51 and leg muscle score remains below average — both lagging indicators. Targeted lower-body resistance work (2×/week) plus continued protein adequacy is the highest-leverage addition over the next 6–8 weeks.

Clinical Interpretation Summary

  • Trajectory confirmed — weight, fat mass, body fat % and trunk fat all moving in the right direction; muscle mass actively increasing
  • High-quality recomposition — fat loss with muscle gain is the gold standard outcome on GLP-1 therapy
  • Tirzepatide hold at 10 mg — current response does not warrant dose escalation; reassess at Scan 5
  • PCOS / insulin-resistance picture still under investigation — working diagnosis remains the most likely underlying mechanism; full blood and methylation results will inform refinement
  • Metabolic age unchanged at 51 — lagging indicator, expected to begin shifting once body composition trend sustains for 8–12 weeks
  • Leg muscle score below age average — primary modifiable target; lower-body resistance training to be layered in
Investigations

Investigations & Protocol Detail

Reference panel of investigations underpinning the current treatment plan

Recommended Investigations

Priority Investigation

Full Stride Blood Panel

Comprehensive blood work to identify underlying hormonal and metabolic issues that may be blocking weight loss.

  • Full thyroid panel (TSH, Free T3, Free T4, thyroid antibodies)
  • Cortisol (AM)
  • Insulin and HbA1c
  • Full lipid panel (total cholesterol, LDL, HDL, triglycerides)
  • Liver function (important with GLP-1 use)
  • Kidney function
  • Full blood count
  • Vitamin D, B12, Folate, Iron studies
  • Female hormones (oestradiol, progesterone, FSH, LH, SHBG, testosterone)
Critical Investigation

Methylation Testing via Stride

MTHFR and methylation panel to identify whether impaired methylation pathways are a key driver behind the metabolic resistance. If Jessica has PCOS combined with poor methylation, this creates a compounding effect where the body cannot properly:

  • Clear excess oestrogen — impaired methylation means the body struggles to metabolise and eliminate hormones, worsening the hormonal imbalance driven by PCOS
  • Process insulin effectively — methylation affects insulin signalling pathways, and if these are compromised it amplifies the insulin resistance that may already be undermining the tirzepatide
  • Produce energy efficiently — the mitochondrial energy cycle depends on methylation; poor methylation means the body converts food to stored fat rather than usable energy
  • Detoxify and reduce inflammation — impaired detox pathways lead to chronic low-grade inflammation, which itself promotes fat storage and further insulin resistance
  • Metabolise statins properly — if methylation pathways are compromised, the liver may struggle to process statins efficiently, potentially amplifying their hormone-suppressing side effects

This test will show us what Jessica’s body isn’t doing properly at a cellular level — and give us a targeted supplementation and lifestyle protocol to correct it.

Clinical Review — Completed 26 Apr

Tirzepatide Efficacy — Hold at 10 mg

With Scan 4 confirming a clear positive trajectory (weight, fat mass and body fat % all falling, muscle mass rising), there is no indication to escalate the GLP-1 dose. Continue tirzepatide at 10 mg. Reassess at Scan 5 (late May). The combined approach — GLP-1 plus insulin-sensitising and methylation support — appears to be the right configuration.

Lifestyle Protocol

Nutrition, Resistance Training & Recovery

Maintain protein at 1.6–2.0 g/kg to protect ongoing muscle gain. Add 2×/week lower-body resistance training to address the leg muscle score. Continue prioritising sleep and stress management — both are required for sustained insulin sensitivity and the metabolic-age improvement we are targeting next.

Clinical sign-off (26 Apr 2026): Dr Gemma Lewis MRCS MRCGP has reviewed Scan 4 alongside the prior three scans and confirmed the current protocol is producing the expected response. Tirzepatide held at 10 mg, supplementation continued, lower-body resistance work added. Next review: Scan 5 in late May 2026.

Next Steps

Next Steps

Sustain the trajectory — layer in resistance work, retest at Scan 5

Next Steps & Roadmap

Completed

Full Stride Blood Panel

Comprehensive blood work completed and reviewed at the 12 April consultation. Findings informed the protocol adjustments now driving the current trajectory.

Done
Completed — 12 Apr 2026

Body Concerns Consultation + Scan 3

Blood panel reviewed with Dr Gemma Lewis. Protocol adjustments agreed (insulin-sensitising support, methylation support, refined nutrition and resistance work). Scan 3 captured.

Done
Completed — 26 Apr 2026

Private GP Appointment + Scan 4

Today: full clinical review with Dr Gemma Lewis. Scan 4 confirms the trajectory has reversed. Tirzepatide held at 10 mg; current protocol continued.

Done
Next 2–4 Weeks

Lower-Body Resistance Programme

Add 2×/week lower-body resistance sessions (squats, hip hinges, lunges, step-ups) to address the leg muscle score and lock in metabolic momentum. Maintain protein at 1.6–2.0 g/kg.

Action: This Week
May 2026

Methylation Panel Results & Refinement

Receive and review methylation panel results. Refine targeted supplementation (B-vitamins, choline, magnesium, inositol) and adjust based on MTHFR variant findings.

Target: Mid-May
Late May 2026

Scan 5 — Trajectory Confirmation

Repeat Tanita scan to confirm the trajectory has held over a further 4–5 weeks. Targeting weight <88 kg, body fat <36%, muscle mass ≥53.5 kg, and the first downward step in metabolic age.

Target: 24 May 2026

Bioelectrical Impedance Data

Segment 6.25 kHz R/X 50 kHz R/X Phase Angle
Hand-to-Leg (H-L) 772.2 / -45.4 662.6 / -77.9 6.74
Right Leg (RL) 321.7 / -21.7 275.2 / -31.7 6.60
Left Leg (LL) 351.8 / -22.6 303.6 / -35.5 5.57
Right Hand (RH) 422.9 / -27.5 367.2 / -41.9 6.54
Left Hand (LH) 405.9 / -28.1 349.0 / -40.6 6.67
Leg-to-Leg (L-L) 680.4 / -42.3 579.0 / -69.4 6.87
Phase angle values indicate cellular health and hydration. Lower left leg phase angle (5.57) may warrant monitoring.
Name: Jessica Gibson
Date of Birth: 28 September 1989
Age: 36 years
Height: 166 cm
Allergies: NKDA (No Known Drug Allergies)
Address: 10 Palmer Close, Branston, Staffordshire, DE14 3DY
Pabau ID (latest): 49456968
Report Date: 26 April 2026
Clinician: Dr Gemma Lewis MRCS MRCGP